4.8 Article

Polytriazoles as copper(I)-stabilizing ligands in catalysis

Journal

ORGANIC LETTERS
Volume 6, Issue 17, Pages 2853-2855

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0493094

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Funding

  1. NIGMS NIH HHS [GM28384] Funding Source: Medline

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Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C-3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.

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