Journal
TETRAHEDRON LETTERS
Volume 45, Issue 35, Pages 6623-6627Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.07.026
Keywords
microwave irradiation; solvent-free synthesis; solid media; quinoline; imide
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Inorganic solid supports are useful media for the rapid and efficient synthesis of a library of quinoline-3,4-dicarboximides. In particular, wet clay K10 was shown to be the best medium for the condensation reaction between 2-methylquinoline3,4-dicarboxylic anhydride and several primary amines. Microwave irradiation is essential for a rapid and complete conversion. (C) 2004 Elsevier Ltd. All rights reserved.
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