Journal
ANALYTICA CHIMICA ACTA
Volume 520, Issue 1-2, Pages 237-243Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.aca.2004.04.069
Keywords
brominated flame retardants; human milk; analysis; PBDEs; TOF
Categories
Ask authors/readers for more resources
In the Czech Republic no study on the levels of brominated flame retardants in human milk has been conducted, yet. In the first step analytical method for determination of PBDEs in this bioindicator matrix was implemented. Liquid-liquid extraction (LLE) (hexane, diethyl ether), followed by gel permeation chromatography was employed for isolation of PBDEs. Identification and quantification of PBDEs was carried out by GC-MS operated in negative chemical ionisation (NCI). Two mass spectrometric technologies, one employing quadrupole and the other one high resolution (HR) time-of-flight (TOF) analyzer, etc. were used in our study. Detection limits (LODs) obtained by quadrupole analyzer ranged from 0.02 to 0.05 ng g(-1) lipid weight, using high resolution time-of-flight analyzer LODs were significantly lower, ranging from 0.002-0.005 ng g(-1) lipid weight, what enabled detection of minor PBDE congeners. Within this pilot study 103 breast milk samples, obtained from mothers living in Olomouc region, were examined. Ten PBDE congeners were determined. All samples examined till now contained PBDEs residues, the dominating contaminant representing this group was congener BDE 47. In most of analysed samples levels of this compound ranged from 0.2 to 2 ng g(-1) of lipid weight. Three exceptionally contaminated samples, containing levels of PBDEs 5-10 times higher than other samples, were found. (C) 2004 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available