4.5 Article

DKT1, a novel K+ channel from carrot, forms functional heteromeric channels with KDC1

Journal

FEBS LETTERS
Volume 573, Issue 1-3, Pages 61-67

Publisher

WILEY
DOI: 10.1016/j.febslet.2004.07.052

Keywords

K+ channel; heteromeric channel; shaker family; Daucus carota

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We report the isolation and characterisation of DKT1, a new carrot K+ channel alpha-subunit belonging to the Shaker-like family. DKT1 is expressed in many tissues of the adult plant, suggesting that it may play important roles in both nutrition and other important physiological processes. During embryo development, DKT1 is expressed at later phases implying the involvement of K+ in embryo maturation. When co-expressed with KDC1 in Xenopus oocytes, DKT1 is able to form functional, heteromeric channels, suggesting that possible interactions between these two ion channels in plant tissues may modulate K+ uptake. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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