Journal
JOURNAL OF FLUORESCENCE
Volume 14, Issue 5, Pages 521-533Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1023/B:JOFL.0000039340.94188.2a
Keywords
continuous glucose monitoring; HPTS; viologen; boronic acid
Ask authors/readers for more resources
In an ongoing program to synthesize a glucose sensing polymer that could be used for real time glucose monitoring in vivo, we have been exploring the use of boronic acid functional viologens as glucose responsive quenchers for fluorescent dyes. The present study focuses on the effect of ionic interactions between pyranine or its various sulfonamide derivatives and the viologen quenchers. Dyes bearing anionic groups were quenched more efficiently when compared to dyes with nonionic substituents. The anionic dyes in conjunction with the cationic quenchers exhibited a broader range of glucose response both in solution and when immobilized in a hydrogel. The interaction of glucose with the sensing components was similar whether they are soluble or immobilized.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available