4.4 Review

Fluorescent chemosensors for carbohydrates: A decade's worth of bright spies for saccharides in review

Journal

JOURNAL OF FLUORESCENCE
Volume 14, Issue 5, Pages 569-584

Publisher

SPRINGER/PLENUM PUBLISHERS
DOI: 10.1023/B:JOFL.0000039344.34642.4c

Keywords

fluorescent probes; saccharides; boronic acids; ICT; PET; FRET

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This review provides a chronological survey of over fifty fluorescent chemosensors for carbohydrates from the period between 1992 to the present. The survey contains only those sensors that are synthetic or chemosensory, utilize boronic acids and display a fluorescence response in the form of intensity changes or shifts in wavelength. With each compound listed, a description of the saccharide probe is given with regard to concentration, excitation and emission wavelengths, pH and solvent mixture proportions. In addition, the selectivity of each chemosensor is provided as well as the trends in binding constants. Where possible, a description of the fluorescence signaling mechanism is given as well as commentary on the probe's unique features within this class of sensors.

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