Journal
APPLIED RADIATION AND ISOTOPES
Volume 88, Issue -, Pages 2-11Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.apradiso.2013.11.109
Keywords
BNCT; Clinical trials; Boron compounds; Accelerators
Categories
Funding
- Hatanaka Award
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The first BNCT trials took place in the USA in the early 1960's, yet BNCT is still far from mainstream medicine. Nonetheless, in recent years, reported results in the treatment of head and neck cancer and recurrent glioma, coupled with the progress in developing linear accelerators specifically for BNCT applications, have given some optimism to the future of BNCT. This article provides a brief reminder on the ups and downs of the history of BNCT and supports the view that controlled and prospective clinical trials with a modern design will make BNCT an evidence-based treatment modality within the coming decade. (C) 2013 Elsevier Ltd. All rights reserved.
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