Journal
JOURNAL OF FLUORESCENCE
Volume 14, Issue 5, Pages 481-489Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1023/B:JOFL.0000039336.51399.3b
Keywords
glucose monitoring; boronic acid; fluorescence sensor
Funding
- NCI NIH HHS [CA88343, N01-CO-27184] Funding Source: Medline
- NIDDK NIH HHS [DK55062] Funding Source: Medline
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Effective management of diabetes relies on the frequent monitoring of blood glucose concentrations. The current approach of blood sampling and glucose concentration determination in vitro presents many problems. Therefore, there is a drive for the development of non-invasive and continuous monitoring of glucose concentrations. The use of implanted glucose fluorescent sensors represents a promising approach. Due to its strong interaction with diol moieties, the boronic acid group often plays a critical role in the design of such glucose sensors. This paper reviews the progress in this area during the last ten years.
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