4.4 Article

A semi-automated system for the routine production of copper-64

Journal

APPLIED RADIATION AND ISOTOPES
Volume 70, Issue 8, Pages 1803-1806

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.apradiso.2012.03.009

Keywords

Copper-64; Isotope production; PET; Automation

Funding

  1. NIH/NCI [R24 CA086307]

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An automated system for the production of high specific activity Cu-64 via the irradiation of electroplated enriched Ni-64 targets has been developed. We have been operating this system continually on a biweekly or weekly basis for more than two years. Since the inception of this automated production system, (October 1, 2008), we have had 145 productions, produced 53562 mCi and shipped out 25629 mCi of this isotope to external users. We routinely produce over 400 mCi of this isotope per batch with a specific activity of 14,000 +/- 7600 mCi/mu mol for distribution to some 12-15 centers each production. (C) 2012 Elsevier Ltd. All rights reserved.

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