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Magnetoresistive-based biosensors and biochips

Journal

TRENDS IN BIOTECHNOLOGY
Volume 22, Issue 9, Pages 455-462

Publisher

ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tibtech.2004.06.006

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Over the past five years, magnetoelectronics has emerged as a promising new platform technology for biosensor and biochip development. The techniques are based on the detection of the magnetic fringe field of a magnetically labeled biomolecule interacting with a complementary biomolecule bound to a magneticfield sensor. Magnetoresistive-based sensors, conventionally used as read heads in hard disk drives, have been used in combination with biologically functionallized magnetic labels to demonstrate the detection of molecular recognition. Real-world bio-applications are now being investigated, enabling tailored device design, based on sensor and label characteristics. This detection platform provides a robust, inexpensive sensing technique with high sensitivity and considerable scope for quantitative signal data, enabling magnetoresistive biochips to meet specific diagnostic needs that are not met by existing technologies.

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