4.3 Article

Secret signatures inside genomic DNA

Journal

BIOTECHNOLOGY PROGRESS
Volume 20, Issue 5, Pages 1605-1607

Publisher

WILEY-BLACKWELL
DOI: 10.1021/bp049917i

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A simple, practical method to watermark short trademarks or signatures into genomic DNA is introduced. Since the marking method is biologically innocuous, it can be applied to all commercialized bacteria to help establish brand names for the engineered strains and to resolve legal disputes regarding gene-related patents. The first such strain of Bacillus subtilis is engineered and is ready to be distributed.

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