Journal
INFECTION AND IMMUNITY
Volume 72, Issue 9, Pages 5506-5510Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.72.9.5506-5510.2004
Keywords
-
Categories
Ask authors/readers for more resources
LuxS plays a role in the synthesis of an extracellular signaling molecule, autoinducer 2 (AI-2). To analyze a possible role of AI-2 in regulating Helicobacter pylori gene expression, we constructed a panel of transcriptional reporter strains. We show that the expression of H. pylori flaA is growth phase dependent and that flaA transcription increases in association with increased culture density. Mutating the luxS gene eliminates growth-phase-dependent control of flaA, and this growth phase dependence is restored when the luxS mutant strain is complemented with the wild-type luxS gene.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available