Journal
MAGNETIC RESONANCE IN MEDICINE
Volume 52, Issue 3, Pages 679-682Publisher
WILEY
DOI: 10.1002/mrm.20178
Keywords
longitudinal relaxation; T-1; 3 tesla; blood; hematocrit; radiation damping
Funding
- NCRR NIH HHS [P41-RR15241] Funding Source: Medline
- NIBIB NIH HHS [P41 EB015909, R21-EB000991] Funding Source: Medline
- NINDS NIH HHS [R01-NS37664] Funding Source: Medline
Ask authors/readers for more resources
It is important to determine the longitudinal relaxation time of blood for black blood imaging, as well as for quantifying blood flow by arterial spin labeling (ASL). In this study a circulation system was used to measure blood T-1 under physiological conditions at the new clinical field strength of 3.0T. It was found that 1/T-1 in s(-1) was linearly dependent (P < 0.05) on hematocrit (Hct) within a normal range of 0.38-0.46. The relationships were 1/T-1 = (0.52 +/- 0.15). Hct + (0.38 +/- 0.06) and 1/T-1 = (0.83 +/- 0.07) Hct + (0.28 +/- 0.03) for arterial (oxygenation = 92% +/- 7%) and venous blood (69% +/- 8%), respectively, which led to estimated T-1 values of 1664 +/- 14 ms (arterial) and 1584 +/- 5 ms (venous) at a typical human Hct of 0.42. The temperature dependencies of blood T-1 were 22.3 +/- 0.6 ms/ degreesC and 19.8 +/- 0.8 ms/degreesC for Hct values of 0.42 and 0.38, respectively. When a head coil transmit/receive setup was used, radiation damping caused a slight reduction (19 ms) of the measured T-1 values. (C) 2004 Wiley-Liss, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available