Journal
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
Volume 39, Issue 4, Pages 514-518Publisher
CANADIAN SCIENCE PUBLISHING, NRC RESEARCH PRESS
DOI: 10.1139/apnm-2013-0430
Keywords
Pax7; IGF-1; acute exercise
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Funding
- NICHD
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Insulin-like growth factor-1 (IGF-1) regulates stem cell proliferation and differentiation in vitro. The aim of this study was to quantify the change in satellite cell (SC) specific IGF-1 colocalization following exercise. We observed a significant increase (p < 0.05) in the percentage of SC with IGF-1 colocalization from baseline to 72 h after a bout of resistance exercise. This strongly supports a role for IGF-1 in human SC function following exercise.
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