4.7 Article

07H239-A, a new cytotoxic eremophilane sesquiterpene from the marine-derived xylariaceous fungus LL-07H239

Journal

JOURNAL OF NATURAL PRODUCTS
Volume 67, Issue 9, Pages 1565-1567

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/np049924g

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07H239-A (1), a new eremophilane sesquiterpene from a marine-derived xylariaceous fungus, was isolated, characterized, and shown to be cytotoxic toward a variety of cancer cell lines, with some selectivity for a CCRFCEM leukemia line (IC50 = 0.9 mug/mL).

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