Journal
IRISH VETERINARY JOURNAL
Volume 57, Issue 9, Pages 525-530Publisher
VETERINARY IRELAND
DOI: 10.1186/2046-0481-57-9-525
Keywords
sheep; pestivirus; border disease; Republic of Ireland; antibody
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Sera from 1,448 adult ewes in 91 Rocks, representing all 26 counties in the Republic of Ireland, were examined for pestivirus antibodies using a commercially available ELISA which detected IgG(1) antibody to border disease virus. Eighty-one sheep (5.6%) in 42 flocks (46.0%) were antibody-positive. Within infected flocks, the mean seroprevalence level was 11.4% with a range of 6.3% to 30.0%. The highest antibody prevalence was detected in sheep from central Lowland counties of Ireland. Comparative neutralisation testing of 42 ELISA-positive sera detected geometric mean antibody titres of 136 to the NADL strain of bovine viral diarrhoea virus (BVDV), 92 to the Moredun strain of border disease virus and 21 to the 137/4 strain of border disease virus. These results suggest that BVDV may be the major ruminant pestivirus infecting sheep in Ireland. Although there are high numbers of infected flocks, many sheep within such flocks remain anti body-negative and are at risk of giving birth to Lambs with congenital border disease.
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