Journal
INFECTION AND IMMUNITY
Volume 72, Issue 9, Pages 5515-5521Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.72.9.5515-5521.2004
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Monoclonal antibodies (MAbs) specific for the P domain of the Plasmodium falciparum PO phosphoriboprotein (PfP0) blocked the invasion of RBCs by P.falciparum. Vaccination with this P-domain peptide protected mice upon malaria parasite challenge. The absolute specificity of the MAbs and the PfP0 P peptide makes them potential protective malaria reagents.
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