4.1 Article

Implications of Epigenetics and Stress Regulation on Research and Developmental Care of Preterm Infants

Journal

Publisher

WILEY-BLACKWELL
DOI: 10.1111/1552-6909.12559

Keywords

behavioral epigenetics; neonatal intensive care unit; preterm birth; stress

Funding

  1. Italian Health Ministry for research on epigenetics mechanisms and early stress in preterm birth
  2. Ricerca Corrente: Studio della reattivita dell'asse ipotalamo ipofisiario in bambini nati fortemente pretermine: fattori genetici e meccanismi epigenetici associati allo stress sociale

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Epigenetics refers to chemical modifications leading to changes in gene expression without any alteration of the DNA structure. We suggest ways through which epigenetic mechanisms might contribute to alter developmental trajectories in preterm infants. Although theoretical and methodological issues still need to be addressed, we discuss how epigenetics might be an emergent research field with potential innovative insights for researchers and clinicians involved in the neonatal care of preterm infants.

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