4.3 Article

Addition reactions of 2-polyfluoroalkyl substituted 1,3-thiazolin-4-one derivatives

Journal

JOURNAL OF FLUORINE CHEMISTRY
Volume 125, Issue 9, Pages 1351-1356

Publisher

ELSEVIER SCIENCE SA
DOI: 10.1016/j.jfluchem.2004.04.003

Keywords

thioamides; dimethyl acetylenedicarboxylate; cycloaddition; thiazoline; dihydropyranothiazole; Diels-Alder

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2-Polyfluoroalkyl-5-methoxycarbonylmethylene-thiazolin-4-ones react as dienophiles on the exo-cyclic ylidene bond to give spiroderivatives and as 1,3-dienes with olefins to give dihydropyranothiazole derivatives. The endo-cyclic C=N bond in these compounds do not enter into the cycloaddition reactions. (C) 2004 Elsevier B.V. All rights reserved.

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