4.6 Article

High sensitivity and high Q-factor nanoslotted parallel quadrabeam photonic crystal cavity for real-time and label-free sensing

Journal

APPLIED PHYSICS LETTERS
Volume 105, Issue 6, Pages -

Publisher

AMER INST PHYSICS
DOI: 10.1063/1.4867254

Keywords

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Funding

  1. Rowland Institute at Harvard
  2. National Natural Science Foundation of China [61372038]
  3. National 973 Program [2012CB315705]
  4. BUPT Excellent Ph.D. Students Foundation, P. R. China [CX201212, CX201331]
  5. China Scholarship Council (CSC) [201206470026]
  6. AFOSR [FA9550-09-1-0669-DOD35CAP]

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We experimentally demonstrate a label-free sensor based on nanoslotted parallel quadrabeam photonic crystal cavity (NPQC). The NPQC possesses both high sensitivity and high Q-factor. We achieved sensitivity (S) of 451 nm/refractive index unit and Q-factor >7000 in water at telecom wavelength range, featuring a sensor figure of merit >2000, an order of magnitude improvement over the previous photonic crystal sensors. In addition, we measured the streptavidin-biotin binding affinity and detected 10 ag/mL concentrated streptavidin in the phosphate buffered saline solution. (C) 2014 AIP Publishing LLC.

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