4.1 Article Proceedings Paper

Visualizing the laboratory mouse: capturing phenotype information

Journal

GENETICA
Volume 122, Issue 1, Pages 89-97

Publisher

SPRINGER
DOI: 10.1007/s10709-004-1435-7

Keywords

database; informatics; mouse; mutagenesis; nomenclature; phenotype; vocabulary

Funding

  1. NHGRI NIH HHS [HG00330] Funding Source: Medline

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A concerted effort to develop myriad new phenotypic alleles through mutagenesis programs presents new challenges for the biomedical community and for the informatics infrastructure needed to support this work. To handle and co-ordinate large programs of treatment, breeding, and sequential or longitudinal testing for a variety of obvious and subtle traits requires sophisticated data management software. Further, trait analyses, heritability testing, and animal availability and status must be captured and disseminated to the wider community. The Mouse Genome Database (MGD) will serve as the central integration point for the various mutagenesis programs, registering new alleles, providing accession identifiers, and capturing phenotypic descriptions. In addition, MGD will provide public access to unified searches over all alleles with links to the centres of origin for detailed testing data.

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