Journal
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
Volume 58, Issue 2, Pages 279-289Publisher
ELSEVIER
DOI: 10.1016/j.ejpb.2004.02.017
Keywords
skin; gel; emulsion; wound dressing; scar treatment; supersaturation; penetration enhancer
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The use of polymers for skin preparations is manifold. Requirements of such polymers are dependent on the formulation types. The most applied polymers on skin belong to various classes, for example to cellulose derivatives, chitosan, carageenan, polyacrylates, polyvinylalcohol, polyvinylpyrrolidone and silicones. They are gelating agents, matrices in patches and wound dressings, anti-nucleants and penetration enhancers. Correlations between commercially available products and results of new scientific investigations are often difficult or not possible, because of the lack of comparative data especially for transdermal patches. Finally, two promising future trends of polymeric systems, gene delivery and tissue engineering, are discussed. (C) 2004 Elsevier B.V. All rights reserved.
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