Journal
SCIENCE
Volume 305, Issue 5689, Pages 1465-1466Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1098109
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Funding
- NCI NIH HHS [CA83716, R01 CA083716] Funding Source: Medline
- NIAMS NIH HHS [R01 AR047364-02, AR47364, R01 AR042177-07, AR42177, R01 AR042177-09, R01 AR042177-08S1, R01 AR042177-10, R01 AR042177-07S1, R01 AR042177-08, R01 AR042177, R01 AR047364-01A2, R01 AR047364-03, R01 AR047364] Funding Source: Medline
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Beak shape is a classic example of evolutionary diversification. Beak development in chicken and duck was used to examine morphological variations among avian species. There is only one proliferative zone in the frontonasal mass of chickens, but two in ducks. These growth zones are associated with bone morphogenetic protein 4 (BMP4) activity. By tinkering with BMP4 in beak prominences, the shapes of the chicken beak can be modulated.
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