4.8 Article

Improved procedure for the oxidative cleavage of olefins by OsO4-NaIO4

Journal

ORGANIC LETTERS
Volume 6, Issue 19, Pages 3217-3219

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0400342

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Oxidative cleavage of olefins by OsO4-NaIO4 Sometimes suffers from low yields due to the formation of side products. It is found that the addition of 2,6-lutidine can suppress the side reactions and dramatically improve the yield of this classic reaction.

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