Catalytic enantioselective conjugate addition of trimethylsilylacetylene to 2-cyclohexen-1-one

The first example of catalytic asymmetric conjugate addition of TMS-acetylene to a cyclic alpha,beta-enone has been accomplished using the chiral bisoxazoline-Ni complex 9 as catalyst and dimethylalumino TMS-acetylide and 2-cyclohexen-1-one as reactants.