4.8 Article

Copper-mediated cross-coupling reactions of N-unsubstituted sulfoximines and aryl halides

Journal

ORGANIC LETTERS
Volume 6, Issue 19, Pages 3293-3296

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol048806h

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Copper-mediated cross-coupling reactions of sulfoximines with aryl iodides and aryl bromides provide N-arylated sulfoximines in high yields. The method is complementary to the known palladium-catalyzed N-arylation and allows the preparation of N-arylated sulfoximines, which have previously been inaccessible.

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