4.4 Article

Gaining diversity in solid-phase synthesis by modulation of cleavage conditions from hydroxymethyl-based supports. Application to lamellarin synthesis

Journal

TETRAHEDRON
Volume 60, Issue 39, Pages 8669-8675

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2004.05.119

Keywords

combinatorial chemistry; diversity; libraries; acidolytic cleavage

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The application of a number of Lewis acids as a cleavage/deprotection method in the solid-phase synthesis of organic molecules can render several analogues, which, after purification, can be submitted for biological evaluation. (C) 2004 Elsevier Ltd. All rights reserved.

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