Modification of microcantilevers using layer-by-layer nanoassembly film for glucose measurement

Here, we report a new approach of glucose measurement by using a multilayer modified microcantilever. Glucose oxidase (GOx)/ polyethyleneimine (PEI) multilayer modified microcantilever underwent bending when it was exposed to glucose solutions. The magnitudes of bending were proportional to the concentrations of glucose. This technique provides a new platform for enzyme functionalized cantilever biosensors. (C) 2004 Elsevier B.V. All rights reserved.