4.7 Article

Practice parameter: Treatment of postherpetic neuralgia an evidence-based report of the Quality Standards Subcommittee of the American Academy of Neurology

Journal

NEUROLOGY
Volume 63, Issue 6, Pages 959-965

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1212/01.WNL.0000140708.62856.72

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A systematic review of the literature on postherpetic neuralgia was performed. The authors identified studies using the National Library of Medicine's Medline database and Cochrane Library database. The authors determined absolute reduction rate, number needed to treat (NNT), 95% CI for NNT, and number needed to harm (NNH) for successful therapies of postherpetic neuralgia. Tricyclic antidepressants, gabapentin, pregabalin, opioids, and lidocaine patch were found to be effective in reducing the pain of postherpetic neuralgia.

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