Preparation of the molecularly imprinted polymers-based capacitive sensor specific for tegafur and its characterization by electrochemical impedance and piezoelectric quartz crystal microbalance

Molecularly imprinted polymers (MIPs)-based capacitive sensor specific for tegafur was constructed by electropolymerization of m-aminophenol onto the surface of gold electrode and the Au-coated quartz crystal electrodes. Electrochemical impedance (EI) and quartz crystal microbalance (QCM) were employed to characterize the modified gold electrodes and the modified Au-coated quartz crystals, respectively. Unlike the capacitive sensors reported in the previous literatures, the present sensors were not treated with alkanethiol after electropolymerization and show even more satisfactory performance. QCM measurements also confirmed the imprinting effect of the polymer layers. (C) 2004 Elsevier Ltd. All fights reserved.