4.8 Article

Amino acid-derived iodobenzene dicarboxylates: Reagents for oxidative conversion of alkenes to amino acid esters

Journal

ORGANIC LETTERS
Volume 6, Issue 20, Pages 3613-3615

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0484714

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New amino acid-derived iodobenzene dicarboxylates were prepared by the reaction of (diacetoxyiodo)benzene with N-protected natural amino acids. These compounds in the presence of iodide anion can be used as reagents for beta-iodocarboxylation of alkenes leading to the respective amino acid esters.

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