Journal
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
Volume 18, Issue 5, Pages 803-812Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.bpobgyn.2004.05.005
Keywords
cardiovascular disease; diabetes; fetal programming; hypertension; lipids; metabolic syndrome; neoplasia
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Metabolic abnormalities and obesity have long been associated with the development of cardiovascular disease in the general population. These same features are also associated with polycystic ovary syndrome (PCOS). An increased prevalence of hypertension, dyslipidaemia, obesity and hyperinsulinaemia, as well as changes in coagulation and blood vessel function, provide an explanation as to why women with PCOS are at an increased risk of developing cardiovascular disease over the long term.
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