Journal
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
Volume 23, Issue 8-9, Pages 1135-1139Publisher
TAYLOR & FRANCIS INC
DOI: 10.1081/NCN-200027391
Keywords
N1-methyl-2-pyridone-5-carboxamide (Me2Py); uraemia; pyridine nucleotide; HPLC; LC/MS
Categories
Ask authors/readers for more resources
We have investigated an unusual nucleotide that accumulates, with precursors, in the erythrocytes of patients in uraemia. This nucleotide is related chemically to the NAD breakdown product, N1-methyl-2-pyridone-5-carboxamide (Me2Py), found in high concentrations in the plasma of uraemic patients. Both Me2Py and the nucleotide accumulate to high concentrations in the blood during uraemia: our investigations of samples from renal out-patients have provided information on a plausible link between the two compounds.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available