Journal
INFECTION AND IMMUNITY
Volume 72, Issue 10, Pages 6185-6189Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.72.10.6185-6189.2004
Keywords
-
Categories
Funding
- MRC [MC_U117532067] Funding Source: UKRI
- Medical Research Council [MC_U117532067] Funding Source: Medline
- Medical Research Council [MC_U117532067] Funding Source: researchfish
Ask authors/readers for more resources
In a cross-sectional survey of 187 Gambian children and adults, we have analyzed prevalence, fine specificity, and 19-kilodalton merozoite surface protein 1 (MSP-1(19))-specific erythrocyte invasion inhibitory activity of antibodies to MSP-1(19) but find no significant association between any of these parameters and prevalence or density of malarial parasitemia, except that, after correcting for total anti-MSP-1(19) antibody levels, individuals with anti-MSP-1(19) antibodies that compete with an invasion inhibitory monoclonal antibody (12.10) were significantly less likely to have malaria infections with densities of greater than or equal to1,000 parasites/mul than were individuals without such antibodies. This association persisted after correction for age and ethnic origin.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available