4.6 Article

Porous silicon nanoparticles as sensitizers for ultrasonic hyperthermia

Journal

APPLIED PHYSICS LETTERS
Volume 103, Issue 19, Pages -

Publisher

AMER INST PHYSICS
DOI: 10.1063/1.4829148

Keywords

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Funding

  1. Russian Foundation for Basic Research [12-02-31266mol_a]
  2. Ministry of Education and Science of the Russian Federation [8737]

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Aqueous suspensions of porous silicon nanoparticles (NPs) with average size similar to 100 nm and concentration similar to 1 g/L undergo significant heating as compared with pure water under therapeutic ultrasonic (US) irradiation with frequencies of 1-2.5MHz and intensities of 1-20 W/cm(2). This effect is explained by taking into account the efficient absorption of US energy by NPs. The observed US-induced heating of biodegradable NPs is promising for applications in ultrasonic hyperthermia of tumors. (C) 2013 AIP Publishing LLC.

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