Journal
JOURNAL OF BIOSCIENCE AND BIOENGINEERING
Volume 98, Issue 4, Pages 304-305Publisher
SOC BIOSCIENCE BIOENGINEERING JAPAN
DOI: 10.1016/S1389-1723(04)00286-5
Keywords
nano-space; chip culture; cell culture
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The minimum size of a closed nano-space in which cells can survive was determined using 4-nl nanowells. One or two cells could divide in the nanowell. Our results suggest that the cell division activity in the nano-space is determined by the conflict between intercellular effects and consumption of substrates.
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