Journal
JOURNAL OF NATURAL PRODUCTS
Volume 67, Issue 10, Pages 1732-1735Publisher
AMER CHEMICAL SOC
DOI: 10.1021/np040114e
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Funding
- NCI NIH HHS [N01-CO-12400] Funding Source: Medline
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Activity-guided fractionation of an Aniba panurensis organic solvent extract has led to the isolation of the novel alkaloid 6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-indolizinium, as the trifluoroacetic acid salt (1). Its structure was determined by NMR and mass spectrometry. Bioassays performed in vitro demonstrated toxicity of compound 1 to a drug-resistant strain of Candida albicans.
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