Journal
MINI-REVIEWS IN MEDICINAL CHEMISTRY
Volume 4, Issue 8, Pages 839-845Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1389557043403288
Keywords
short chain fatty acids; butyrate; inflammation; cancer; colon and fiber
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Short chain fatty acids (SCFA) have multiple in vivo and in vitro effects including cell cycle arrest and induction of protein synthesis, differentiation, and apoptosis. Butyrate or derivatives have promise for treating inflammatory bowel disease and colon cancer. Genomic and proteomic analysis have generated new knowledge on function and applications for SCFA.
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