4.2 Article

Alcoholic ketoacidosis associated with multiple complications: Multiple report of 3 cases

Journal

INTERNAL MEDICINE
Volume 43, Issue 10, Pages 955-959

Publisher

JAPAN SOC INTERNAL MEDICINE
DOI: 10.2169/internalmedicine.43.955

Keywords

metabolic acidosis; anion gap; 3-hydroxybutyric acid

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We report 3 patients with alcoholic ketoacidosis (AKA). All had a history of excessive intake and abrupt termination of alcohol. They showed tachypnea, tachycardia, abdominal tenderness, and epigastralgia. Metabolic acidosis with an increased anion gap, decreased PaCO2 and ketonemia were present. One patient whose ratio of 3-hydroxybutyric acid to acetoacetic acid was 4.0 was associated with diabetic ketoacidosis. All patients were successfully hydrated with electrolyte, glucose and thiamine. Complications such as liver dysfunction, lactic acidosis, acute pancreatitis, Wernicke's encephalopathy, rhabdomyolysis and heart failure were present. Attention should be paid to multiple complications in the treatment of AKA.

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