Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 42, Issue 10, Pages 4815-4817Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.42.10.4815-4817.2004
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We have determined the in vitro susceptibilities of 57 strains of Cryptococcus gattii to nine antifungal agents and have compared the MICs for these strains with those for C. neoformans. MICs were determined by a microdilution reference method. Albaconazole and ravuconazole (MICs of 0.04 and 0.05 mug/ml, respectively) showed the best activities. Micafungin showed no activity (MIC of > 128 mug/ml). In general, C. gattii was less susceptible than C. neoformans to all drugs tested, with the exception of amphotericin B and flucytosine.
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