Journal
HEREDITY
Volume 93, Issue 4, Pages 399-403Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/sj.hdy.6800516
Keywords
mitochondrial DNA; PCR-RFLP; paternal inheritance; microsatellite markers
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The mitochondrial DNA of 172 sheep from 48 families were typed by using PCR-RFLP, direct amplification of the repeated sequence domain and sequencing analysis. The mitochondrial DNA from three lambs in two half-sib families were found to show paternal inheritance. Our findings provide direct evidence of paternal inheritance of mitochondria DNA in sheep. A total of 12 highly polymorphic microsatellite markers, which mapped on different chromosomes, were employed to type the sheep population to confirm family relationships. Possible mechanisms of paternal inheritance are discussed.
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