Journal
TETRAHEDRON LETTERS
Volume 45, Issue 41, Pages 7719-7721Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2004.08.112
Keywords
protection; aldehydes; ruthenium; chemoselective
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A convenient method for the chemoselective protections of both aliphatic and aromatic aldehydes has been developed. Ruthenium(III) trichloride (0.1 mol%) has found to be an highly efficient catalyst in the acetalizations of aldehydes with various simple alcohols such as methanol, ethanol, or diols such as 1,2-ethylanediol and 1,3-propanediol under mild reaction conditions. (C) 2004 Elsevier Ltd. All rights reserved.
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