Journal
APPLIED PHYSICS LETTERS
Volume 100, Issue 1, Pages -Publisher
AMER INST PHYSICS
DOI: 10.1063/1.3672035
Keywords
-
Categories
Funding
- NSF [CBET-0744040]
- U.S. EPA [R834092]
- NIH [ES019311]
- EPA [150154, R834092] Funding Source: Federal RePORTER
- Directorate For Engineering
- Div Of Chem, Bioeng, Env, & Transp Sys [0744040] Funding Source: National Science Foundation
Ask authors/readers for more resources
The physical interaction between a lipid vesicle and a silver nanoparticle (AgNP)-human serum albumin (HSA) protein corona has been examined. Specifically, the binding of AgNPs and HSA was analyzed by spectrophotometry, and the induced conformational changes of the HSA were inferred from circular dichroism spectroscopy. The fluidity of the vesicle, a model system for mimicking cell membrane, was found to increase with the increased exposure to AgNP-HSA corona, though less pronounced compared to that induced by AgNPs alone. This study offers additional information for understanding the role of physical forces in nanoparticle-cell interaction and has implications for nanomedicine and nanotoxicology. (C) 2012 American Institute of Physics. [doi: 10.1063/1.3672035]
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available