4.8 Article

Application of phosphine-oxazoline ligands in Ir-catalyzed asymmetric hydrogenation of acyclic aromatic N-arylimines

Journal

ORGANIC LETTERS
Volume 6, Issue 21, Pages 3825-3827

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol048399+

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(GRAPHICS) A new class of chiral phosphine-oxazoline ligands have been developed. Chiral Ir complexes prepared from these ligands induced high enantioselectivities (66-90% ee) when applied to the asymmetric hydrogenation of acyclic aromatic N-arylimines.

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