Journal
ORGANIC LETTERS
Volume 6, Issue 21, Pages 3759-3762Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol048502v
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(GRAPHICS) A practical synthesis Of beta-L-3'- and beta-L-5'-O-levulinyl-2'-deoxynucleosides has been described for the first time through enzymatic acylation and/or hydrolysis processes. It is noteworthy that the different behavior exhibited by Pseudomonas cepacia lipase in the acylation of D- and L-nucleosides allows the parallel kinetic resolution Of D/L-nucleosides.
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