4.8 Article

Highly regioselective nucleophilic carbon-carbon bond formation on furans and thiophenes initiated by Pumerer-type reaction

Journal

ORGANIC LETTERS
Volume 6, Issue 21, Pages 3793-3796

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol0484310

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(GRAPHICS) The reactions of (phenyLsulfinyl)furans or -thiophenes with carbon nucleophiles in the presence of trifluoroacetic anhydride allowed the nucleophilic installation of carbon functional groups on the furan and thiophene nuclei with complete regioselectivity.

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