4.7 Article

Synthesis of (-)-9,10-epi-stemoamide

Journal

JOURNAL OF ORGANIC CHEMISTRY
Volume 69, Issue 22, Pages 7734-7736

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/jo049083i

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Funding

  1. NIGMS NIH HHS [GM 26568] Funding Source: Medline

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An efficient synthesis of (-)-9,10-epi-stemoamide has been accomplished in nine steps and 13% overall yield. The synthesis features a lithium hydroxide-promoted fragmentation and an intramolecular 7-exo-trig radical cyclization.

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