Journal
RADIOLOGY
Volume 233, Issue 2, Pages 596-602Publisher
RADIOLOGICAL SOC NORTH AMERICA
DOI: 10.1148/radiol.2332031676
Keywords
heart, MR; magnetic resonance (MR), comparative studies; magnetic resonance (MR), contrast enhancement; myocardium, infarction
Funding
- NHLBI NIH HHS [R29HL-47405, HL-4590, N01-HC95161] Funding Source: Medline
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Strain-encoded magnetic resonance (MR) imaging was prospectively evaluated for direct imaging of systolic myocardial strain and compared with cross-registered delayed contrast material-enhanced MR imaging in five healthy volunteers and nine patients with infarction. Local contractile performance was decreased in infarcted myocardium versus that in remote and adjacent myocardium (P <.01) and in adjacent versus remote myocardium (P <.05). The extent of dysfunctional myocardium, as assessed with strain-encoded MR imaging, was greater than that of hyperenhancement, as assessed with delayed contrast-enhanced MR imaging (P <.05). Strain values obtained with strain-encoded MR imaging were strongly correlated with those obtained with three-dimensional tagged MR imaging (r = 0.75, P <.001). Strain-encoded MR imaging provides spatially resolved (1.5 x 2.5-mm) imaging and measurement of myocardial strain in humans without the need for postprocessing, which may improve routine comprehensive evaluation of myocardial viability. (C) RSNA, 2004.
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