Journal
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
Volume 15, Issue 6, Pages 971-975Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0103-50532004000600027
Keywords
amino alcohols; enamino ketones; oxazines; stereoselective reduction
Categories
Ask authors/readers for more resources
Reduction of beta-enamino ketones 2 with NaBH4 in glacial acetic acid gave gamma-amino alcohols 1 in 70% to 98% yield with diastereomeric excesses, preferentially the syn product, from 44% to 90%. The stereochemistry of these compounds was confirmed by analysis of their tetrahhydro-1,3-oxazine derivatives 3.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available