Journal
JOURNAL OF FLUORESCENCE
Volume 14, Issue 6, Pages 677-679Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1023/B:JOFL.0000047217.74943.5c
Keywords
radiative decay engineering; metal-enhanced fluorescence; solution assays
Funding
- NCI NIH HHS [R43 CA097569, 1 R43-CA97569-01] Funding Source: Medline
- NCRR NIH HHS [P41 RR008119] Funding Source: Medline
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In recent years our laboratories have reported the favorable effects for fluorophores placed in close proximity to surface immobilized silver nanostructures. These include; greater quantum yields, reduced lifetimes (increased photostability) and directional emission. However, while these findings are likely to find multifarious applications for surface assays based on enhanced fluorescence detection, a solution based enhanced sensing platform has yet to be realized. In this short, note, we show how SiO2-coated silver colloids, indeed provide for a solution based enhanced fluorescence sensing platform with a 3-5 fold enhancement typically observed.
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